Let's talk Omphalocele This is another type of anterior abdominal wall defect. -With an omphalocele, organs like the intestines and liver herniate through the umbilical cord and are covered/protected by a thin membrane/sac. -Most cases are sporadic, but it is a feature of many genetic syndromes -The prognosis depends on the size of herniation, presence, or absence of other birth defects, and presence or absence of underlying genetic concerns. -With a small omphalocele, a vaginal delivery can be
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The typical radiological feature of cavernous malformations (CMs) is popcorn appearance and haemorrhagic rim. These benign non-neoplastic vascular lesions are seen in approximately 0.5% of people. CMs are composed of dilated thin-walled capillaries with an endothelial lining; contrary to historic teaching, intervening neuroparenchyma can be seen on histology. 80% are sporadic and 20% familial. The familial CM syndromes are caused by mutations in CCM1 (KRIT1), CCM2 (MGC4607), or CCM3 (PDCD10). Co
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