
Pathology Outlines - Erythroid maturation (erythropoiesis)
Aug 1, 2012 · Early erythroid precursors cluster in islands randomly distributed throughout marrow but related to vascular structures Erythroblast (pronormoblast) islands may be specialized …
Pathology Outlines - Parvovirus (erythrovirus) B19
Dec 1, 2006 · Marked erythroblast hypoplasia, immature giant erythroblasts Occasional erythroblasts may have intranuclear inclusions with surrounding rim of residual chromatin
Pathology Outlines - Parvovirus B19
May 1, 2016 · Parvovirus B19 is spread by respiratory droplets, and has an incubation period of 5 - 14 days Viral receptor is the erythrocyte P antigen, which is expressed on endothelial cells …
Pathology Outlines - Iron in nonneoplastic marrow
Oct 1, 2013 · Macrophage and erythroblast cytoplasm Erythroblasts with ferritin Clumped, vesticle and free ferritin Erythroblast with a clump of ferritin Iron in mitochondria Erythroblast containing …
Pathology Outlines - AML M6
Nov 4, 2025 · Acute erythroid leukemia (AEL) or pure erythroid leukemia (PEL) is a neoplastic proliferation of erythroid cells with features of maturation arrest (increased proerythroblasts) …
Pathology Outlines - Myeloperoxidase (MPO)
Jan 25, 2024 · Myeloperoxidase (MPO) is a myeloid marker that stains neutrophils strongly and other granulocytes variably.
Pathology Outlines - Megaloblastic anemia
Oct 11, 2021 · Megaloblastic anemia is a disorder of impaired DNA synthesis (with normal RNA synthesis) that manifests with the presence of megaloblasts in the bone marrow resulting in …
Pathology Outlines - General
Sep 1, 2012 · Cells with multilineage hematopoietic differentiation potential and sustained self renewal activity Detected by their ability to regenerate long term multilineage hematopoiesis in …
Pathology Outlines - CD61
Feb 27, 2024 · CD61 is a membrane glycoprotein that associates with CD41 to form a heterodimeric complex (CD61 / CD41); dominant integrin on platelets that is essential for …
Pathology Outlines - MDS with biallelic TP53 inactivation
Sep 3, 2024 · MDS with biallelic TP53 inactivation is a new myelodysplastic neoplasm subtype per WHO 5th edition and ICC 2022; it is characaterized by increased blast counts, higher risk …