The ex-defence secretary replaces Rachel Reeves, while Ed Miliband becomes Foreign Secretary and Shabana Mahmood remains Home Secretary.

Andy Burnham jettisoned some of predecessor Sir Keir Starmer’s allies as he handed John Healey the key economic brief.

The yield on 10-year Government bonds, called gilts, moved eight basis points higher to 5.049 at the end of London trading.

Sjogren’s disease affects around half a million people in the UK, with women making up 90 of adults diagnosed with the condition.