Major Finding: V(D)J recombination–derived excised DNA circles replicate and are associated with BCP-ALL relapse. Concept: Excised signal circle (ESC) persistence in relapsed BCP-ALL promotes ESC–RAG ...

Authors may opt to publish their research under an open access license in any of the AACR hybrid journals. The hybrid AACR journals include: Blood Cancer Discovery; Cancer Discovery; Cancer ...

1Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University ...