Final 53-man roster decisions now loom for the Indianapolis Colts. All teams must have their initial 53-man rosters set by 4:00 PM ET on Tuesday. So, with about six weeks' worth of information from training camp, two joint practices, and three preseason games, here is how we see the Colts ' final 53-man roster shaking out.

The Indianapolis Colts concluded their 2025 preseason in dominant fashion, defeating the Cincinnati Bengals on the road 41-14. With plenty on the line when discussing the 53-man roster, there was a lot to see in this game despite the starters sitting.