From memory formation to disease prevention, scientists are uncovering how chromatin structure, enzyme evolution, and epigenetic regulators orchestrate gene activity. Recent breakthroughs reveal how ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still ...

Discover research from St. Jude identifying PHIP as a novel dependency in cancers that have mutations in SWI/SNF ...

DNA is packaged inside cells with the double helix tightly coiled around histone proteins (yellow) that form nucleosomes. These are then coiled together and further packaged into chromosomes (far ...

KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.

This interesting study presents important information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations ...