Genetic information in cancer cells reveals the strength of cancer–immune interactions in an individual-based stochastic model, which captures explicit interactions between cancer and effector cells.

Machine learning with whole-cell patch-clamp and local field potential recordings reveals that synaptic responses from five mossy cells, despite their limited population, can significantly reconstruct ...

Using all-atom simulations of model mycomembranes, the work reports compelling structural insights into how α-mycolic acids and outer leaflet lipids (PDIM and PAT) shape membrane organisation. The ...

Models were more consistent than individual experts but performed comparably to ensembles of many experts and relative performance varied by month, justifying the use of combined model and expert ...

Introducing premature visual experience by opening the closed eyelids early in ferrets caused many cells in the primary visual cortex to mature improperly.

Imperial College London and the University of Sheffield have signed up to eLife’s uncapped scheme in support of a more open, equitable and sustainable science publishing system.

Individual retinal ganglion cells are singularly activated in the living primate retina via an adaptive optics scanning light ophthalmoscope.

Spatiotemporal analysis of global kelch13 surveillance data reveals that artemisinin resistance is increasing in East Africa, mirroring patterns previously observed in Southeast Asia.

Rapid, combined and personalized non-invasive stimulation of the precuneus improves associative memory, enhances local gamma expression, and strengthens precuneus–hippocampal connectivity.

The rate of acquisition of genomic changes in cancer has been the topic of much discussion, with several recent investigations finding evidence of punctuated evolution instead of gradual accumulation ...

Overview of the process of obtaining genomic diversity of influenza virus in a population replicated from a single particle. (a) MDCK cells were infected with influenza vi ...

The dorsal vagal complex is a highly intricate structure composed of distinct transcriptional classes of glial and neuronal cells, exhibiting many similarities but also notable differences between ...