BMJ

Development of a preliminary composite disease activity index in psoriatic arthritis

1 Department of Rheumatology, St Vincent's University Hospital, University College Dublin, Dublin, Ireland 2 Department of Dermatology, St Vincent's University Hospital, Dublin, Dublin, Ireland ...
BMJ

AB0067 Allosteric receptor modulation of a free fatty acid receptor turns natural agonists into potent activators of the superoxide generating neutrophil nadph-oxidase

Background Short chain fatty acids are generated in the colon by bacterial fermentation of dietary fibres and serve as natural agonists for the free fatty acid receptor 2 (FFA2R/GPR43) which belongs ...
BMJ

EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part I ...

Correspondence to Dr Nicolino Ruperto, Paediatric Rheumatology International Trials Organisation (PRINTO), IRCCS G Gaslini, Università di Genova, Pediatria II – Reumatologia, EULAR Centre of ...
BMJ

EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjögren's syndrome

Objectives To develop a score for assessment of patients' symptoms in primary Sjögren's syndrome (SS): the EULAR SS Patient Reported Index (ESSPRI). Methods Dryness, pain, somatic and mental fatigue ...
BMJ

PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome

Objectives Autoantibodies are used clinically to phenotype and subset patients with autoimmune rheumatic diseases. We detected a novel 60 kDa autoantibody specificity by immunoblotting using a ...
BMJ

FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment

Objective: To analyse the distribution of FOXP3+CD25+CD4+ regulatory T cells (Treg) in peripheral blood, synovial fluid and tissue of patients with rheumatic disease during relapse and after local ...
BMJ

Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to ...

Background: Optimal use of disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis is vital if progression of disease is to be reduced. Methotrexate (MTX) and sulfasalazine (SASP) are ...
BMJ

Intracellular and extracellular CPPD crystals are a regular feature in synovial fluid from uninflamed joints of patients with CPPD related arthropathy

Objectives: To determine whether calcium pyrophosphate dihydrate (CPPD) crystals can be found in the synovial fluid of non-inflamed joints in patients with CPPD related arthropathy; if so, to ...
BMJ

Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time

1 Department of Medicine, Division of Clinical Immunology and Rheumatology, School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA 2 Department of Surgery, Section of ...
BMJ

Thickness of human articular cartilage in joints of the lower limb

OBJECTIVES (a) To determine the topographical variations in cartilage thickness over the entire surfaces of cadaveric lower limb joints, and (b) to examine the correlations between: cartilage ...
BMJ

The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by ...

Rheumatology, Med Klinik I, Charité, Campus Benjamin Franklin, Berlin, Germany ...
BMJ

Assessment of outcome in ankylosing spondylitis: an extended radiographic scoring system

1 Department of Rheumatology, University Medical Centre St Radboud, Nijmegen, The Netherlands 2 Department of Rheumatology, St Maartenshospital, Nijmegen, The Netherlands 3 Department of Medical ...