Follow along with score and in-game updates as the Bills face the Colts on Sunday afternoon at Lucas Oil Stadium.

Much is at stake between the Buffalo Bills and Indianapolis Colts on Sunday ... A $10 bet would make $134.72. James Cook over ...

James Cook and the Buffalo Bills meet the Indianapolis Colts on Sunday at 1 p.m. ET at Lucas Oil Stadium.In terms of points ...

To help us preview the Indianapolis Colts’ Week 10 matchup with Buffalo, Bills Wire answered five key questions to provide ...

Before James Cook and his teammates take the field Sunday at 1:00 PM ET on CBS, there will be numerous player prop bets ...

Bills quarterback Josh Allen has been the heart of this Bills squad, throwing for 2,001 passing yards, 17 touchdowns, and ...

Buffalo Bills running back James Cook bounces off a would-be tackler for 20-yard rush against the Indianapolis Colts. New England Patriots quarterback Drake Maye finds tight end Austin Hooper for a 28 ...

Buffalo will clearly have an eye on Week 11 when they host the Kansas City Chiefs. Hopefully, Amari can hit his stride for ...

Buffalo Bills kicker Tyler Bass' 29-yard field goal gives the Bills the early 10-0 lead over the Indianapolis Colts.

For a team that’s had plenty of question marks before the season, the Buffalo Bills are defying the odds. Week 6 win. Week 7 ...

The Indianapolis Colts have the second-worst run defense in the NFL right now, allowing 149.8 yards on the ground per game. Running back James Cook and company should be ready to capitalize on that.

James Cook accumulated 27.5 fantasy points -- 11 carries, 78 yards, 2 TDs; 1 reception, 17 yards, 1 TD -- in his best game of the season. That was in Week 2 versus the Miami Dolphins. Cook picked up 4 ...