Two of the 49ers captains had differing opinions when speaking to the media, including Kittle firing back at some of Bosa's comments.

The San Francisco 49ers' season came to an end with yet another disappointing loss as they fell 47-24 to the Arizona Cardinals on Sunday. The once stout 49ers defense allowed the Cardinals to score six touchdowns on them, capping off the year with a game that sums up their unfortunate 6-11 season.

George Kittle, Nick Bosa and Colton McKivitz are not among the seven players inactivated before the 49ers’ season finale at Arizona