See what Kyle Shanahan, Joshua Dobbs, Jonathan Gannon and Kyler Murray had to say following the Week 18 contest.

In the 49ers' finale against the Cardinals, head coach Kyle Shanahan delegated play-calling duties to Klay Kubiak, who led the offense to 436 total yards.

The wide receiver took a few knocks in the defeat to the Lions on New Year’s Eve. He missed all of the Niners' practices last week.

Out of the postseason race, the San Francisco 49ers and Arizona Cardinals are preparing to start backups because of injuries for their season-ending matchup Sunday in Glendale, Ariz.

San Francisco 49ers QB Joshua Dobbs and LB Fred Warner reacted to the 49ers season finale against the Arizona Cardinals.

The San Francisco 49ers' final game of the season in the NFL will likely be without Deebo Samuel, and Kyle Shanahan addressed the wide receiver's future.

The Cardinals were driving for the go-ahead touchdown in the final minute before the Rams picked off a deflected pass by Murray to secure a 13-9 win. The 49ers led for much of their game against the Detroit Lions — one of the NFL's best teams — before falling 40-34.

The San Francisco 49ers just lost 47-24 to the Arizona Cardinals. Here are the 49ers' grades for this performance.

Among those listed as “out” Friday by 49ers coach Kyle Shanahan were wide receiver Deebo Samuel (rib/wrist), cornerback Deommodore Lenoir (shoulder), quarterback Brock Purdy (shoulder), tackle Spencer Burford (calf) and defensive end Ronald Beal (ankle).

The San Francisco 49ers wrapped up their season with a 47-24 loss to the Arizona Cardinals, falling to 6-11 in their second-to-worst finish under head coach Kyle Shanahan. It was a tight battle through the first half,

Kyle Shanahan has high expectations for quarterback Joshua Dobbs entering San Francisco's regular-season finale against the Arizona Cardinals.