Presentations highlight AI-driven mRNA design process enabling up to 40-fold selectivity and 10-fold in vivo oncoselectivity ...

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting ...

Four of nine patients responded to the mesothelin-directed therapy, which uses a multi-chain receptor borrowed from NK cells, ...

Pre-wired ability in ‘resting’ T cells to remember past viral foes discovered, a promising breakthrough for targeted cancer therapies. A team of immunologists at the University of Massachusetts ...

The body’s “killer” T cells don’t just attack—they strike with astonishing precision, forming a tiny, highly organized ...

A major bottleneck in curing HIV (human immunodeficiency virus) is that the virus can hide in an inactive form within resting white blood cells, which play a crucial role in coordinating the immune ...

By deploying a "tag and sort" fix using E3 ligases, scientists successfully cleared the protein buildup and restored T-cell ...

The immune system is the frontline protection against infection, continually searching for and destroying unknown pathogens.

Cytotoxic T cells are star players in the adaptive immune system, enforcing protection against invading viruses or cancer cells. However, evidence has been mounting that the cells may also deal a ...