EurekAlert!

Accurate cell type annotation for single-cell chromatin accessibility data via contrastive learning and reference guidance

Chromatin accessibility, a fundamental property of DNA that plays a critical role in gene regulation and cell identity, refers to the degree that nuclear macromolecules can access and interact with ...
EurekAlert!

MultiKano: an automatic cell type annotation tool for single-cell multi-omics data based on Kolmogorov-Arnold network and data augmentation

MultiKano is the first automatic cell type annotation method tailored to single-cell multi-omics data. MultiKano introduces a novel data augmentation strategy based on paired scRNA-seq and scATAC-seq ...
technologynetworks

Cell Type Annotation in Spatial Datasets

Cell type annotation is the step at which spatial transcriptomics data becomes interpretable biology, converting expression matrices into labeled tissue maps. The challenge is sharpened by limited ...
News Medical

GPT-4 shows expert-level accuracy in annotating cell types

Columbia University's Mailman School of Public HealthMar 26 2024 Reviewed GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing -- a sequencing process ...