The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...

Understanding why cancer cells rely on specific genes is critical for designing effective targeted therapies. A new study ...

A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated ...

A new study reveals how a single cancer protein may simultaneously drive tumor survival and metabolic control, uncovering a ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk ...