Allyl isothiocyanate, the pungent principle of wasabi and other mustard oils, produces pain by activating TRPA1, an excitatory ion channel on sensory nerve endings. Isothiocyanates are ...
Professor Xiaokong Liu's team at Jilin University proposed an "activation-quenching" strategy for dynamic covalent chemistry, achieving precise and controllable "on-off" switching of dynamic bond ...
Pirtobrutinib met the primary endpoint of response rate non-inferiority, favoring pirtobrutinib with a nominal P-value for superiority < 0.05 Progression-free survival data was immature, but trending ...
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