Poly(ADP-ribose) (PAR) is synthesized from NAD + by PAR polymerases (PARPs) and regulates many physiological processes such as the maintenance of DNA integrity, gene expression and cell division.
Poly(ADP-ribosyl)ation (PARylation) is a post-translational modification in which ADP-ribose units are added to Glu, Asp and Lys residues of target (or acceptor) proteins by members of the ...
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