USA Today's NFL experts make their picks for a Week 16 showdown between the Indianapolis Colts and San Francisco 49ers

Ravens | Bengals | Browns | Steelers AFC South: Texans | Colts | Jaguars | Titans AFC West: Broncos | Chiefs | Raiders | Chargers NFC East: Cowboys | Giants | Eagles | Commanders NFC North: Bears | Lions | Packers | Vikings NFC South: Falcons | Panthers | Saints | Buccaneers NFC West:

In 2026, Henderson irons out his issues in blitz pickup and runs more patiently, posting a 1,000-yard season as the Patriots’ new full-time back. He might even push for a top spot on the franchise’s all-time single-season rushing board (Corey Dillon leads with 1,645 yards in 2004).

An inside look at Sunday’s Jets-Patriots NFL Week 17 matchup at MetLife Stadium: