Accelerated repetitive transcranial magnetic stimulation appears to be effective for treatment-resistant depression.

The approval of medicines called second-generation antipsychotics has allowed major depressive disorder (MDD) and other conditions linked to it to be treated. A person with MDD is usually prescribed ...

CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal ...

Major depressive disorder (MDD) is a disturbance of mood that may have persistent and long-term consequences impacting patients’ overall level of functioning and quality of life. 1 Historically, ...

Breakthrough study finds single dose of psychedelics significantly reduced depression symptoms in clinical trial, with ...

—Researchers recently examined the impact of depressive symptoms, as measured by the 21-item Beck Depression Inventory, on adherence to therapy using correlation, network analysis, and linear ...

Older adults dealing with depression often face compounding challenges when they become intensely fearful of their own ...

Johnson & Johnson’s oral add-on drug significantly improved depressive symptoms and sleep outcomes in a phase 3 trial for patients who previously did not benefit from antidepressants alone. The ...

DMT therapy significantly reduced major depressive disorder symptoms in a phase IIa trial. Learn more about this rapid-acting psychedelic approach.

Data are limited, however. In mice, ingesting exercise mimetics appeared to improve depressive-like behaviors, and the ...

In an early clinical trial, a single dose of a short-acting psychedelic drug led to rapid improvement in people with major depressive disorder.