Cook should get a chance to win with league rushing title. The Colts play at 1 p.m. Sunday and the Bills don't play until ...

The Buffalo Bills haven’t had an NFL rushing leader since O.J. Simpson in 1976, but James Cook is on the doorstep. Cook took ...

Buffalo Bills running back James Cook could face a big challenge from Baltimore Ravens back Derrick Henry for the league ...

Cook is among the top fantasy performers at his position, with 267.7 fantasy points (16.7 per game). That ranks him fifth at ...

Coach Sean McDermott has been coy about his approach to Sunday's lineup, but he conceded Cook's chase was on his mind.

James Cook has been unstoppable all season for the Buffalo Bills and could hit a major milestone as early as Week 17.

With Buffalo Bills' veterans reporting to training camp on Tuesday, all eyes are on running back James Cook, who is a holdout candidate as he seeks a new contract from the team. Well, a big question ...

Buffalo Bills running back James Cook has agreed to a four-year, $48 million extension with the franchise, which includes $30 million guaranteed, per ESPN's Adam Schefter and multiple reports. Cook ...

ORCHARD PARK, N.Y. — James Cook was prepared to continue his hold-in. "However long it took," Cook said. "But we got it done so. We don't need to be discussing that and let's play football. And now, ...

James Cook and Dalvin Cook are brothers. Most people know that, that the Buffalo Bills ' standout RB and former Minnesota Vikings ' star runner are connected in that way. But there's another, deeper ...

Running backs Derrick Henry and Saquon Barkley signed contract extensions this offseason. Could James Cook be the next running back to ink a new deal? There’s growing optimism Cook and the Bills can ...

Learn more about for James Cook's prop betting lines, stats and more before his Buffalo Bills play against the Philadelphia ...