Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to be associated with neurodegenerative disorders. Corresponding author Kai ...

Scientists at UC Riverside uncovered evidence that compounds beyond THC may influence how the body regulates metabolism and insulin signaling.

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

The c-Jun N-terminal kinases (JNKs) form a subgroup of mitogen-activated protein kinases that respond to metabolic and inflammatory stress signals. In obesity, excess nutrients and adipose tissue ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

Study: Personalized molecular signatures of insulin resistance and type 2 diabetes. Image credit: Microgen/Shutterstock.com A recent study, published in the journal Cell, utilized cutting-edge ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Growing evidence suggests it takes a sustained viral infection in the right genetic environment to lead to type 1 diabetes.