Large molecule biotherapeutics are primarily expressed and produced in mammalian host cells then purified from complex mixtures containing growth media and host cell material. Identifying, monitoring, ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

When a virus infects a bacterial cell, the viral genome is the first component to be fully injected into the cell, making it an ideal immune target. A bacterial enzyme anchored to the membrane ...

Sartorius launched a new genetically engineered CHO host cell line that the company says improves productivity and efficiency. The team leveraged proteomic profiling and targeted genome editing to ...

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the ...

Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large ...