Our results support a role for DYRK1A as the relevant target of the harmine analogs and probably exclude closely related kinases such as DYRK1B, DYRK2, DYRK3, DYRK4, and CLKs 1–4. For example, DYRKs 3 ...

University of Virginia School of Medicine scientists have identified a potential way to improve heart function after heart attacks—and it could involve a drug extracted from plants commonly used as ...

Human neural progenitors exposed to harmine, an alkaloid presented at the psychotropic plant decoction ayahuasca, led to a 70 percent increase in proliferation of these cells. The effect of generating ...

Diabetes researchers and bioinformaticians from the Icahn School of Medicine at Mount Sinai have developed a new understanding of how human beta cell regenerative drugs work. These drugs, developed at ...

Please provide your email address to receive an email when new articles are posted on . A drug derived from a flowering plant found in the Middle East and in some South American vines appears to drive ...

Harmine: Future Diabetes Drug Class? A novel drug candidate, harmine, can trigger human insulin-producing beta cells to multiply, new research has shown. A novel drug candidate, harmine, can trigger ...

After screening hundreds of compounds for their effects on fat development, researchers have discovered that an ingredient found in some plants fights diabetes in mice without some of the side effects ...