Auburn travels to face off against Baylor in a pivotal Week 1 matchup at McLane Stadium in Waco, Texas. The Tigers are suffering through one of the worst stretches in program history after posting four straight losing seasons for the first time since 1950. Before the 2022 season, the Tigers had made a bowl game every year since 2013.

The 2025 college football season kicks off overseas with the Aer Lingus College Football Classic between No. 17 Kansas State and No. 22 Iowa in State in Dublin, Ireland.