A seminal paper by Miller and Brody [1] clearly laid the general framework on why we should abandon the term "clinical equipoise" in research. Their paper argued that the concept of equipoise (also ...
Long-Term Follow-Up of the Prospective Randomized AATT Study (Autologous or Allogeneic Transplantation in Patients With Peripheral T-Cell Lymphoma) Novel cancer drugs can produce higher and more ...
In this issue of the Journal of Clinical Oncology, Saltz et al 1 report the results of Cancer and Leukemia Group B (CALGB) 89803, a prospective randomized phase III trial of adjuvant therapy for ...
Freedman justified this by saying: "[I]t is necessary that the clinical investigator be in a state of genuine uncertainty regarding the comparative merits of treatments A and B for a population. If a ...
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