Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with ...

Warsaw breakage syndrome (WABS) is caused by defective DDX11, a DNA helicase that is essential for chromatid cohesion. Here, a paired genome-wide siRNA screen in patient-derived cell lines reveals ...

Two RIKEN researchers have discovered how, during cell division, one enzyme helps facilitate the tightly coordinated reorganization of chromosomal DNA into compact structures that can be evenly ...