Highlights from the Week 2 matchup between the Detroit Lions and the Buffalo Bills during the 2026 NFL season.

A new era will begin in Buffalo when the Bills host the Detroit Lions on Thursday night. The new Highmark Stadium will play host to its first regular-season game, as the Bills said goodbye to their previous home for 53 seasons at the end of the 2025 season.

The Buffalo Bills hosted the Detroit Lions in their first game at their new home, Highmark Stadium. Here are all the highlights from Bills vs. Lions in Buffalo.

Josh Allen threw for 334 yards and accounted for four touchdowns as the Buffalo Bills escaped Houston with a 36-31 win over the Texans.

ORCHARD PARK, N.Y. (WIVT/WBGH) – The Buffalo Bills got the win last night in their first regular season game at the new Highmark Stadium, beating the Detroit Lions 41-31. Quarterback Josh Allen had an incredible night,

The Bills' Super Bowl curse rolls on despite incredible QB play from Josh Allen.

Buffalo Bills defensive tackle Ed Oliver suffered an injury in warmups before the game against the Lions on Thursday, Sept. 17, 2026.

Detroit Lions quarterback Jared Goff's best throws from his four-touchdown game vs. the Buffalo Bills during Week 2 of the 2026 NFL season. Detroit Lions running back Jahmyr Gibbs' best plays from his 113-yard game vs. the Buffalo Bills during Week 2 of the 2026 NFL season.

Josh Allen and the Bills host the Detroit Lions to kick off Week 2 on "Thursday Night Football." USA TODAY Sports is providing live updates here: