Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the ...

New findings challenge previous assumptions about nitric oxide in Alzheimer’s disease, and point to potential new therapeutic ...

RNA is the means of translating the genetic code embedded in DNA into proteins, which serve as enzymes, transporters, ...

Alternative splicing (AS) is a key technique for increasing transcriptome and proteomic diversity from a small genome. Almost all human gene transcripts are alternatively spliced, resulting in protein ...

A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and ...

What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...

In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Pancreatic cancer ...

A new AI-based system combines genomic sequences and RNA-binding protein profiles to model complex RNA splicing patterns ...

Computational biologists have uncovered how RNA splicing -- a crucial process for isoform expression and protein diversity -- is regulated across different cell types in the peripheral blood. This ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...