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WEB2 days ago · Open Heart is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from protocols to phase I trials to meta-analyses, including small or specialist studies. Opinionated discussions on controversial ...
Four pillars of heart failure: contemporary ... - Open Heart
WEBThe past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF).1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a background of an ageing and increasingly ...
Vitamin K2—a neglected player in cardiovascular health: a …
WEBVitamin K2 serves an important role in cardiovascular health through regulation of calcium homeostasis. Its effects on the cardiovascular system are mediated through activation of the anti-calcific protein known as matrix Gla protein. In its inactive form, this protein is associated with various markers of cardiovascular disease including increased arterial stiffness, vascular and valvular ...
Acute myocarditis caused by COVID-19 disease and following …
WEBCOVID-19: from subclinical myocardial injury to fulminant lethal myocarditis. SARS-CoV-2 gains entry into human cells by binding its cleaved spike protein (S1/S2 and S2ʹ sites) to the ACE2 membrane protein,1 which, can be found on ciliated columnar epithelial cells of the respiratory tract, type II pneumocytes and also cardiomyocytes.2 Since, failed human hearts have a higher percentage of ...
Authors - Open Heart
WEBOpen Heart is an online-only open access journal dedicated exclusively to publishing cardiology research. The journal aims to provide rapid publication of research through a continuous publication model. As well as publishing definitive articles, Open Heart will consider protocols. All articles published in Open Heart will have been sent for peer review.
Transcatheter mitral valve repair: an overview of current and future ...
WEBThe field of transcatheter mitral valve repair (TMVr) for mitral regurgitation (MR) is rapidly evolving. Besides the well-established transcatheter mitral edge-to-edge repair approach, there is also growing evidence for therapeutic strategies targeting the mitral annulus and mitral valve chordae. A patient-tailored approach, careful patient selection and an experienced interventional team is ...
About - Open Heart
WEBOpen Heart is an online-only, open access cardiology journal that is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or ...
Mechanisms of ECG signs in chronic obstructive pulmonary disease
WEBObjective Patients with chronic obstructive pulmonary disease (COPD) often have abnormal ECGs. Our aim was to separate the effects on ECG by airway obstruction, emphysema and right ventricular (RV) afterload in patients with COPD. Methods A cross-sectional study was performed on 101 patients with COPD without left heart disease and 32 healthy age-matched controls. Body mass index (BMI) was ...
Decreasing the omega-6/3 ratio decreases inflammation - Open …
WEBThe consumption of seed oils high in the omega-6 polyunsaturated fat (PUFA) linoleic acid (LA) contributes to low-grade inflammation, oxidative stress, endothelial dysfunction and atherosclerosis.1 Moreover, dietary LA significantly increases cyclooxygenase-2 (COX-2) expression in the aorta,2 converting arachidonic acid (AA) to proinflammatory eicosanoids. This may explain why increasing LA ...
Cardiac and obstetric outcomes in pregnant women with heart …
WEBObjective To appraise the application of the 2018 European Society of Cardiology-adapted modified WHO (mWHO) classification to pregnant women with heart disease managed at our maternal–fetal medicine referral centre and to assess whether the lack of a multidisciplinary Pregnancy Heart team has influenced their outcomes. Methods A retrospective cohort study including all pregnancies with ...